Personalised medicine: Problems of translation into the human domain

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Standard

Personalised medicine : Problems of translation into the human domain. / Vogt, Henrik; Green, Sara.

De-Sequencing. Identity work with genes. ed. / D. Mahr; Martina von Arx. London : Palgrave Macmillan, 2020. p. 19-48.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Harvard

Vogt, H & Green, S 2020, Personalised medicine: Problems of translation into the human domain. in D Mahr & M von Arx (eds), De-Sequencing. Identity work with genes. Palgrave Macmillan, London, pp. 19-48. https://doi.org/10.1007/978-981-15-7728-4_2

APA

Vogt, H., & Green, S. (2020). Personalised medicine: Problems of translation into the human domain. In D. Mahr, & M. von Arx (Eds.), De-Sequencing. Identity work with genes (pp. 19-48). Palgrave Macmillan. https://doi.org/10.1007/978-981-15-7728-4_2

Vancouver

Vogt H, Green S. Personalised medicine: Problems of translation into the human domain. In Mahr D, von Arx M, editors, De-Sequencing. Identity work with genes. London: Palgrave Macmillan. 2020. p. 19-48 https://doi.org/10.1007/978-981-15-7728-4_2

Author

Vogt, Henrik ; Green, Sara. / Personalised medicine : Problems of translation into the human domain. De-Sequencing. Identity work with genes. editor / D. Mahr ; Martina von Arx. London : Palgrave Macmillan, 2020. pp. 19-48

Bibtex

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title = "Personalised medicine: Problems of translation into the human domain",
abstract = "This chapter explores translational challenges in the era of precision or personalised medicine, which is also called “P4 medicine”. It argues that preventive strategies within the P4 (personalised, predictive, preventive, participatory) framework may aim to translate {\textquoteleft}risks{\textquoteright} into benefit without a real target audience in mind; that is, in ways that do not fit personal and societal contexts, or that are premature. In this way, it risks resulting in waste and harm. To improve this situation, the authors argue that the challenges that human-level complexity poses for personalised medicine should be better accounted for, also in initial phases of medical translation.",
author = "Henrik Vogt and Sara Green",
year = "2020",
doi = "10.1007/978-981-15-7728-4_2",
language = "English",
pages = "19--48",
editor = "Mahr, {D. } and {von Arx}, Martina",
booktitle = "De-Sequencing. Identity work with genes",
publisher = "Palgrave Macmillan",
address = "United Kingdom",

}

RIS

TY - CHAP

T1 - Personalised medicine

T2 - Problems of translation into the human domain

AU - Vogt, Henrik

AU - Green, Sara

PY - 2020

Y1 - 2020

N2 - This chapter explores translational challenges in the era of precision or personalised medicine, which is also called “P4 medicine”. It argues that preventive strategies within the P4 (personalised, predictive, preventive, participatory) framework may aim to translate ‘risks’ into benefit without a real target audience in mind; that is, in ways that do not fit personal and societal contexts, or that are premature. In this way, it risks resulting in waste and harm. To improve this situation, the authors argue that the challenges that human-level complexity poses for personalised medicine should be better accounted for, also in initial phases of medical translation.

AB - This chapter explores translational challenges in the era of precision or personalised medicine, which is also called “P4 medicine”. It argues that preventive strategies within the P4 (personalised, predictive, preventive, participatory) framework may aim to translate ‘risks’ into benefit without a real target audience in mind; that is, in ways that do not fit personal and societal contexts, or that are premature. In this way, it risks resulting in waste and harm. To improve this situation, the authors argue that the challenges that human-level complexity poses for personalised medicine should be better accounted for, also in initial phases of medical translation.

UR - https://link.springer.com/chapter/10.1007/978-981-15-7728-4_2

U2 - 10.1007/978-981-15-7728-4_2

DO - 10.1007/978-981-15-7728-4_2

M3 - Book chapter

SP - 19

EP - 48

BT - De-Sequencing. Identity work with genes

A2 - Mahr, D.

A2 - von Arx, Martina

PB - Palgrave Macmillan

CY - London

ER -

ID: 226545344